Manual on immunohistochemical diagnosis of human tumors. - 4th ed. - Petrov S.V.

Manual on immunohistochemical diagnosis of human tumors. - 4th edition - Petrov S.V.
The book provides a summary of the results of immunohistochemical studies of most human tumors. It describes the basic principles and algorithms of immunohistochemical histogenetic diagnosis of human neoplasms, as well as describes their main predictive and prognostic markers. The detailed immunohistochemical characteristics of tumors of the lymph and hematopoiesis system, soft tissues, breast, skin, lung, stomach, colon, liver, pancreas and thyroid glands, adrenal glands, pituitary gland, kidneys, bladder, prostate, testes, uterus, ovaries, peripheral and central nervous system, etc. are given.
Modern data on the neuroendocrine system, mechanisms of apoptosis, cell cycle rate, molecular and genetic features of a number of malignant tumors are presented. Basic information on molecular-biological methods of morphological diagnostics of pre-tumor conditions and malignant neoplasms is given on the example of hybridization and PCR in situ. Considerable attention is paid to quality control, difficulties in immunohistochemical detection of the cellular source of neoplasm in metastatic lesions, and the peculiarities of the method.
The monograph is intended for pathologists, cytologists, oncologists, senior students of medical universities, as well as for medical scientists and biologists involved in the study of human tumors